Even though Priorat DOQ covers a small area, there are several different micro-climates present. Generally, the climate is more extreme than most continental climate areas, though there is a marked contrast between the valleys and the higher areas. There are both freezing winds from the north (mitigated somewhat by the Montsant mountain) and also the warm Mistral wind from the east.
Summers are long, hot and dry (max temperature 35°) while winters are cold (min temperature -4 °C). There is the occasional risk of frost, hailstones and drought. The average annual temperature is 15 °C, and average annual rainfall is 400–600 mm.